Venom Genomics and Proteomics
Springer | Toxinology | Jan. 6 2016 | ISBN-10: 9400764154 | 454 pages | pdf | 10.3 mb
Editors: Gopalakrishnakone, P., Calvete, Juan J. (Eds.)
Complete and comprehensive overview of toxinology
Written by a very large team of experts from all around the world
Covers all areas of toxinology, including topics like bioterrorism, toxin evolution and toxin based drug development
About this Reference Work
This volume provides the reader with recent advances in the fields of molecular toxinology, the biotechnological applications of venom toxins, and antivenom production. The content of the twenty chapters of illustrates not only the enormous progress made since the implementation of omics technologies in the field of toxinology, but one also realizes the road still ahead to reach a holistic view of venomous systems. Advancement in high-throughput technologies in the field of venomics has resulted in the ability to generate comprehensive venom profiles for many species. However, research on snake genomes is still in its infancy, although such studies are eagerly awaited to gain insights into the evolutionary history of snake venom proteins, including the mechanisms that originated venom and the regulation of toxin expression. Fortunately, this objective is also at the reach of current omic technologies. Therefore it would not be unrealistic to predict a bright near future to the field of molecular toxinology.
covers research into the venom of scaled reptiles (lizards and snakes), scorpions, spiders, ants and platypuses. Special consideration is given to a number of observations made in the area of snake venom and in the application of advanced genomics and proteomics techniques on a variety of venom samples. The final chapters give some insight into the potential clinical uses of venom derivatives and into the importance and challenges faced in the production and quality control of antivenoms.
Number of Illustrations and Tables
16 illus., 64 in colour
Pharmaceutical Sciences / Technology
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